化工社化工社 化学情報印刷レポート · 研究参考用
Oxalyl chloride → 2-Acetoxypropionyl Chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Oxalyl chloride | HCID 65578 | — |
| 反応物 | 2-Acetoxypropionic Acid | HCID 79041 | — |
| 生成物 | 2-Acetoxypropionyl Chloride | HCID 4547492 | — |
反応手順
Stir a mixture of 2-acetoxy-propionic acid (550 g, 4.16 mol) in oxalyl chloride (500 mL) at room temperature for overnight. After removal of oxalyl chloride under vacuum, ˜700 g crude product is obtained (quantitative yield crude), which is used directly in the next step. 1H NMR (CDCl3, 400 MHz): δ 5.16 (m, 1H), 2.13 (s, 3H), 1.58 (d, J=7.2, 3H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08648081B2 |
| 出典データセット | uspto-grants-2014_02 |
| ORD ID | ord-d1f45a29329b409e8b9910c2a4ebf546 |
| 出典メモ | uspto-grants-2014_02 |