Pyridine-2-carboximidamide hydrochloride → 4-Chloro-6,6-dimethyl-2-(pyridin-2-yl)-5,6,7,8-tetrahydroquinazoline

HRID 241008

反応式

HRID 241008 の反応式
O[C:2]1[CH2:7][CH2:6][C:5]([CH3:9])([CH3:8])[CH2:4][C:3]=1[C:10]([O-])=O.[ClH:13].[N:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[C:20](=[NH:22])[NH2:21]>>[Cl:13][C:10]1[C:3]2[CH2:4][C:5]([CH3:9])([CH3:8])[CH2:6][CH2:7][C:2]=2[N:21]=[C:20]([C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][N:14]=2)[N:22]=1

参加物

3

反応物 2

HCID 12403615Pyridine-2-carboximidamide hydrochlorideHCID 178425726HCID 178425726、化合物

生成物 1

HCID 866478144-Chloro-6,6-dimethyl-2-(pyridin-2-yl)-5,6,7,8-tetrahydroquinazoline

実験手順

Synthesized according to the method of reagent preparation 8 by using 2-hydroxy-5,5-dimethylcyclohex-1-enecarboxylate and picolinimidamide hydrochloride in step 2. MS (ES) for C15H16ClN3: 274 (MH+).

後処理

  1. customSynthesized
  2. customaccording to the method of reagent preparation 8

出典と根拠

ORDレコード
ord-846fb0e8081144d38d3731b4a9a27fae
出典データセット
uspto-grants-2014_02
特許番号
US08648066B2

関連ノート

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