3-Chloropropanesulphonyl chloride → Methyl 4-[1-(1,1-dioxo-1lambda6-isothiazolidin-2-yl)-1-methylethyl]benzoate
反応式
[NH2:1][C:2]([C:5]1[CH:14]=[CH:13][C:8]([C:9]([O:11][CH3:12])=[O:10])=[CH:7][CH:6]=1)([CH3:4])[CH3:3].Cl[CH2:16][CH2:17][CH2:18][S:19](Cl)(=[O:21])=[O:20]>>[O:20]=[S:19]1(=[O:21])[CH2:18][CH2:17][CH2:16][N:1]1[C:2]([C:5]1[CH:14]=[CH:13][C:8]([C:9]([O:11][CH3:12])=[O:10])=[CH:7][CH:6]=1)([CH3:3])[CH3:4]参加物
3
実験手順
Using methyl 4-(1-amino-1-methylethyl)benzoate (570 mg) and 3-chloropropane-1-sulfonyl chloride (0.47 mL) and by the reaction and treatment in the same manner as in Preparation Example 17, the title compound (862 mg) was obtained.
後処理
- customby the reaction and treatment in the same manner
- customas in Preparation Example 17
出典と根拠
- ORDレコード
- ord-56068c774a014b379e91b2179bd9beef
- 出典データセット
- uspto-grants-2014_08
- 特許番号
- US08816079B2
反応ノート
読み込み中…