1-(3,5,6-Trimethylpyridin-2-yl)piperazine → HCID 86676770、化合物
反応式
[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[C:4]([CH3:11])[N:3]=1.[CH3:12][C:13]1[C:14]([N:21]2[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]2)=[N:15][C:16]([CH3:20])=[C:17]([CH3:19])[CH:18]=1>>[Br:1][C:2]1[N:3]=[C:4]([CH3:11])[C:5]([C:6]([N:24]2[CH2:25][CH2:26][N:21]([C:14]3[C:13]([CH3:12])=[CH:18][C:17]([CH3:19])=[C:16]([CH3:20])[N:15]=3)[CH2:22][CH2:23]2)=[O:8])=[CH:9][CH:10]=1参加物
3
実験手順
Using 6-bromo-2-methylnicotinic acid (745 mg) and 1-(3,5,6-trimethylpyridin-2-yl)piperazine (744 mg) described in Preparation Example 92 and by the reaction and treatment in the same manner as in Preparation Example 111, the title compound (801 mg) was obtained.
後処理
- customdescribed in Preparation Example 92 and by the reaction and treatment in the same manner as in Preparation Example 111
出典と根拠
- ORDレコード
- ord-bc26cdaed84441f68bcbf6c12ae08ce2
- 出典データセット