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Sodium Hydroxide → 4-(Buta-1,3-dienyl)-2-fluoro-1-triphenylmethylimidazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Allyltriphenylphosphonium bromide | HCID 197740 | — |
| 反応物 | 2-Fluoro-1-trityl-1H-imidazole-4-carbaldehyde | HCID 53779028 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 4-(Buta-1,3-dienyl)-2-fluoro-1-triphenylmethylimidazole | HCID 54446174 | — |
反応手順
2-Fluoro-4-formyl-1-triphenylmethylimidazole was reacted with allyl triphenyl phosphonium bromide in CH2Cl2 in the presence of aqueous NaOH to give 4-(buta-1,3-dienyl)-2-fluoro-1-triphenylmethylimidazole having the following n.m.r. spectrum in CDCl3 : 5.06-5.39 (m, 2H); 5.87 (d, 1H); 6.06 (dd, 1H); 6.49 (s, 1H); 7.51 and 7.7 (d of t, 3H); 7.08-7.44 (br, 15H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04492692 |
| 出典データセット | uspto-grants-1985_01 |
| ORD ID | ord-7a76a7f448324455a663cb68ee5447d0 |
| 出典メモ | uspto-grants-1985_01 |