HCID 178493728、化合物 → HCID 178512636、化合物
反応式
[NH:1]([C:5]1[S:6][CH:7]=[C:8]([CH2:10][CH2:11][CH2:12][CH2:13][NH2:14])[N:9]=1)[C:2]([NH2:4])=[NH:3].[NH:15]([C:19]1[S:20][CH:21]=[C:22]([CH2:24][CH2:25][CH2:26][CH2:27][NH:28][C:29]2[C:32](=O)[C:31](=[O:34])[C:30]=2[O:35]C)[N:23]=1)[C:16]([NH2:18])=[NH:17]>CO>[NH:1]([C:5]1[S:6][CH:7]=[C:8]([CH2:10][CH2:11][CH2:12][CH2:13][NH:14][C:32]2[C:31](=[O:34])[C:30](=[O:35])[C:29]=2[NH:28][CH2:27][CH2:26][CH2:25][CH2:24][C:22]2[N:23]=[C:19]([NH:15][C:16]([NH2:18])=[NH:17])[S:20][CH:21]=2)[N:9]=1)[C:2]([NH2:4])=[NH:3]参加物
4
実験手順
A mixture of 2-guanidino-4-(4-aminobutyl)thiazole (0.105 g) and 1-[4-(2-guanidinothiazol-4-yl)butylamino]-2-methoxycyclobutene-3,4-dione (0.16 g) in dry methanol (5 ml) was stirred for 18 hours at room temperature. The white solid was filtered off, washed with methanol and dried in vacuo to give 1,2-bis[4-(2-guanidinothiazol-4-yl)butylamino]cyclobutene-3,4-dione, 0.16 g., m.p. 228°-229° C.
後処理
- filtration