4-(1,3-Thiazol-2-yl)benzaldehyde → (4-(Thiazol-4-yl)phenyl)methanol
反応式
[S:1]1[CH:5]=[C:4]([C:6]2[CH:13]=[CH:12][C:9]([CH:10]=[O:11])=[CH:8][CH:7]=2)[N:3]=[CH:2]1.S1C=CN=C1C1C=CC(C=O)=CC=1>>[S:1]1[CH:5]=[C:4]([C:6]2[CH:7]=[CH:8][C:9]([CH2:10][OH:11])=[CH:12][CH:13]=2)[N:3]=[CH:2]1参加物
3
実験手順
Reaction and post-treatment were carried out in the same manner as in Reference Example 4-(a) except for using 4-(thiazol-4-yl)benzaldehyde (1.28 g, 6.76 mmol) obtained in Reference Example 15-(a) in place of 4-(thiazol-2-yl)benzaldehyde to afford the title compound (1.07 g) as a white solid. (Yield: 83%)
後処理
- customReaction
出典と根拠
- ORDレコード
- ord-93107596b21b4af3809dd8fb75a5d599
- 出典データセット
- uspto-grants-2014_02
- 特許番号
- US08648097B2
反応ノート
読み込み中…