Boron tribromide → 4-Chloro-2-(4-hydroxyphenylamino)benzoic acid

反応式

[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([O:18]C)=[CH:14][CH:13]=2)[CH:3]=1.B(Br)(Br)Br>>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([OH:18])=[CH:14][CH:13]=2)[CH:3]=1

参加物

反応物 2

HCID 25134Boron tribromide

HCID 666744-Chloro-2-((4-methoxyphenyl)amino)benzoic acid

生成物 1

HCID 4254234-Chloro-2-(4-hydroxyphenylamino)benzoic acid

実験手順

4-Chloro-2-(4-hydroxyphenylamino)benzoic acid [XI; R=4Cl, R"=H, OH at 4-position] was prepared by reaction of 4-chloro-2-(4-methoxyphenylamino)benzoic acid with boron tribromide according to the procedure of Example 3, part (b), and obtained as a gray solid, m.p. 164°-165° C.

後処理

customobtained as a gray solid, m.p. 164°-165° C.

出典と根拠

ORDレコード: ord-480b9b5a069a44bf9376734dad3fd196
出典データセット: uspto-grants-1985_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04496590

反応ノート

読み込み中…