HCID 73181603、化合物 → 2-Chloro-6,7-dimethoxyquinoline-3-carbonitrile
反応式
[Cl:1][C:2]1[C:11]([CH:12]=[N:13]O)=[CH:10][C:9]2[C:4](=[CH:5][C:6]([O:17][CH3:18])=[C:7]([O:15][CH3:16])[CH:8]=2)[N:3]=1>C(OC(=O)C)(=O)C>[Cl:1][C:2]1[C:11]([C:12]#[N:13])=[CH:10][C:9]2[C:4](=[CH:5][C:6]([O:17][CH3:18])=[C:7]([O:15][CH3:16])[CH:8]=2)[N:3]=1参加物
3
実験手順
To 112 g of 2-chloro-6,7-dimethoxy-3-quinolinecarboxaldehyde oxime was added 1000 ml of acetic anhydride. The mixture was stirred at reflux for 3 hours and then cooled to room temperature. The precipitate which formed was separated by filtration, washed with hot ethanol, and then dried to give 2-chloro-6,7-dimethoxy-3-quinolinecarbonitrile melting at about 223.5°-224.5° C.
後処理
- temperatureat reflux for 3 hours
- customThe precipitate which formed
- customwas separated by filtration
- washwashed with hot ethanol
- customdried
出典と根拠
- ORDレコード
- ord-24974996c63b4fc1b9801a585d39208d
- 出典データセット
- uspto-grants-1985_01
- 特許番号
- US04496725
反応ノート
読み込み中…