N-[(6-Methoxypyridin-2-yl)methyl]acetamide → (6-Methoxypyridin-2-yl)methanamine
反応式
C([NH:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH3:13])[N:7]=1)(=O)C.Cl.NCC1C=CC=C(OC)N=1.Cl.NCC1NC(=O)C=CC=1>Cl>[NH2:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH3:13])[N:7]=1参加物
5
実験手順
The crude product, 2-acetamidomethyl-6-methoxypyridine from Part A, was combined with 10 ml of 6N hydrochloric acid, and the resulting mixture was heated at its reflux temperature for about 16 hours. The mixture was evaporated to provide a tan solid residue. The product was determined by infrared and nuclear magnetic resonance spectral analyses to be a mixture of 2-aminomethyl-6-methoxypyridine hydrochloride and 6-aminomethyl-2(1H)-pyridone hydrochloride.
後処理
- temperaturethe resulting mixture was heated at its
- temperaturereflux temperature for about 16 hours
- customThe mixture was evaporated
- customto provide a tan solid residue
出典と根拠
- ORDレコード
- ord-f5b161a1df44478c97059ee14f21eb70
- 出典データセット
- uspto-grants-1985_01
- 特許番号
- US04496734
反応ノート
読み込み中…