Triethylamine → HCID 178458073、化合物

HRID 2413344

反応式

HRID 2413344 の反応式
[S:1]([NH:5][C:6](=[NH:12])[CH2:7][CH2:8]S(C)=O)(=[O:4])(=[O:3])[NH2:2].C(N(CC)CC)C>C(O)C>[S:1]([NH:5][C:6](=[NH:12])[CH:7]=[CH2:8])(=[O:4])(=[O:3])[NH2:2]

参加物

4

反応物 2

HCID 8471TriethylamineHCID 1785046403-methylsulfinyl-N'-sulfamoylpropanimidamide

生成物 1

HCID 178458073HCID 178458073、化合物収率 97%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A suspension of N-sulfamyl-3-(methylsulfinyl)propionamidine (5.0 g, 23.5 mmol) in ethanol (100 ml) containing triethylamine (3.6 ml) was refluxed for 20-40 hours. Upon cooling, suspended solids were removed by filtration and the solvent evaporated to give a residue (3.4 g) which was chromatographed on silica gel and eluted with 3-7% methanol/chloroform. Upon concentration of appropriate fractions, the title compound crystallized to give 1.3 g, mp 72°-75°.

後処理

  1. temperaturewas refluxed for 20-40 hours
  2. temperatureUpon cooling
  3. customwere removed by filtration
  4. customthe solvent evaporated

出典と根拠

ORDレコード
ord-6a761a7d15e94fce851f6dee349aa910
出典データセット
uspto-grants-1985_01
特許番号
US04496737

関連ノート

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