(Ethoxycarbonylmethyl)triphenylphosphonium → HCID 53853771、化合物

HRID 2413450ノート

反応式

HRID 2413450 の反応式
C[O-].[Na+].[Cl:4][C:5]1[CH:6]=[N:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[C:10]([Cl:15])[C:9]=2[CH:16]=[O:17].[CH2:18]([O:20][C:21]([CH2:23][P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)=O)[CH3:19]>CO.C(O)C>[Cl:4][C:5]1[CH:6]=[N:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[C:10]([Cl:15])[C:9]=2[C:16](=[O:17])[CH:19]=[CH:18][O:20][CH2:21][CH3:23]

参加物

6

反応物 3

HCID 73732(Ethoxycarbonylmethyl)triphenylphosphoniumHCID 10942334Sodium MethoxideHCID 13090787HCID 13090787、化合物

生成物 1

HCID 53853771HCID 53853771、化合物

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 887Methanol溶媒

実験手順

36 ml of a 15% strength solution of sodium methylate in methanol were added dropwise, at 20° C., to a suspension of 22.6 g of 3,7-dichloro-8-formylquinoline and 38.4 g of ethoxycarbonylmethyl-triphenyl-phosphonium chloide in 200 ml of ethanol. The mixture was stirred for 3 hours, after which the precipitate was filtered off under suction, washed with water and dried.

後処理

  1. filtrationafter which the precipitate was filtered off under suction
  2. washwashed with water
  3. customdried

出典と根拠

ORDレコード
ord-0601905ab212409aaa373c77feecf319
出典データセット
uspto-grants-1988_01
特許番号
US04717416

反応ノート

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