Acetic Acid → HCID 54127815、化合物

HRID 2413451ノート

反応式

HRID 2413451 の反応式
C[O-].[Na+].[Cl:4][C:5]1[CH:6]=[N:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[C:10]([Cl:15])[C:9]=2[CH:16]=O.[CH3:18][C:19]([C:21]1[CH:22]=[CH:23][C:24]([OH:27])=[CH:25][CH:26]=1)=O.[Cl-].C1([PH+](C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C(O)(=O)C>CO.C(O)C>[Cl:4][C:5]1[CH:6]=[N:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[C:10]([Cl:15])[C:9]=2[CH:16]=[CH:18][CH2:19][C:21]1[CH:26]=[CH:25][C:24]([OH:27])=[CH:23][CH:22]=1

参加物

7

反応物 4

HCID 176Acetic AcidHCID 10942334Sodium MethoxideHCID 13090787HCID 13090787、化合物HCID 86741956HCID 86741956、化合物

生成物 1

HCID 54127815HCID 54127815、化合物

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 887Methanol溶媒

反応条件

温度
20 °C

実験手順

36 ml of a 15% strength solution of sodium methylate in methanol were added to 11 g of 3,7-dichloro-8-formylquinoline and 21.6 g of 4-hydroxyacetophenone-triphenylphosphonium chloride in 150 ml of ethanol. The mixture was stirred for 21/2 hours at 20° C., after which 3 ml of glacial acetic acid were added and the precipitate was filtered off under suction, washed with water and dried.

後処理

  1. filtrationthe precipitate was filtered off under suction
  2. washwashed with water
  3. customdried

出典と根拠

ORDレコード
ord-e7e2b04f662f42a8a83157e311725dcc
出典データセット
uspto-grants-1988_01
特許番号
US04717416

反応ノート

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