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Water → 6-Methoxy-2-n-octyl-1,2,3,4-tetrahydroisoquinoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 6-Methoxy-2-capryloyl-1,2,3,4-tetrahydroisoquinoline | HCID 20155809 | — |
| 反応物 | Aluminium lithium hydride | HCID 21226445 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 6-Methoxy-2-n-octyl-1,2,3,4-tetrahydroisoquinoline | HCID 20155816 | — |
反応手順
The amide prepared under (a) is dissolved in 50 ml of dry diethyl ether and added dropwise to a suspension of 1.0 g of lithium aluminum hydride in 100 ml of dry diethyl ether. The mixture is then heated under reflux for 3 hours, 5 ml of water is added cautiously to cause decomposition, with cooling, and inorganic material is filtered off. The oil remaining after removal of the solvent in vacuo is reac-ted further without purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04717724 |
| 出典データセット | uspto-grants-1988_01 |
| ORD ID | ord-354151d8ec2c420c9e7fe1115fc350ce |
| 出典メモ | uspto-grants-1988_01 |