化工社化工社 化学情報印刷レポート · 研究参考用
Ethanol → 2-Acetylpyridine 4-(2-morpholinoethyl)thiosemicarbazone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | 2-Acetylpyridine | HCID 14286 | — |
| 反応物 | 3-Amino-1-(2-(morpholin-4-yl)ethyl)thiourea | HCID 736209 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 2-Acetylpyridine 4-(2-morpholinoethyl)thiosemicarbazone | HCID 54402859 | — |
反応手順
A mixture of 6.00 g (0.0294 mole) of 4-(2-morpholinoethyl)thiosemicarbazide, 3.91 g (0.0323 mole) of 2-acetylpyridine, 20 mL of 95% ethanol, and 0.4 mL of glacial acetic acid was heated under reflux for 1.25 hours. The mixture then stood overnight at room temperature. Colourless crystals were collected and recrystallised from 40 mL of 95% ethanol; yield 7.81 g (86%) of pale yellow crystals of 2-acetylpyridine 4-(2-morpholinoethyl)thioseicarbazone, mp 167.5°-169° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04719221 |
| 出典データセット | uspto-grants-1988_01 |
| ORD ID | ord-a7071a5459f34bbc99fc2494dadebae9 |
| 出典メモ | uspto-grants-1988_01 |