Methanol → N-(2-Amino-2-oxoethyl)-2,2-dimethyl-5-oxo-1-imidazolidineacetamide
反応式
[C:1](O)(=O)[CH3:2].[NH2:5][CH2:6][C:7]([NH:9][CH2:10][C:11]([NH:13][CH2:14][C:15]([NH2:17])=[O:16])=[O:12])=[O:8].[CH3:18]O>CC(C)=O>[CH3:18][C:1]1([CH3:2])[NH:5][CH2:6][C:7](=[O:8])[N:9]1[CH2:10][C:11]([NH:13][CH2:14][C:15]([NH2:17])=[O:16])=[O:12]参加物
4
実験手順
To a solution of glycylglycylglycinamide acetate (800 mg) in methanol (8 ml) and acetone (15 ml), Amberlite IRA-68 resin (2 ml) was added. The suspension was stirred at room temperature for 1 hour, then the resin was filtered off and the solution was evaporated under reduced pressure. The residue was suspended in acetone and stirred at room temperature overnight. The precipitate was collected and crystallized from ethyl acetate, to give the title compound, as a white powder, m.p. 102°-105° C. dec.