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Acetic Acid → 4-methyl-2,7-diphenyl-1H-pyrazolo[3,4-b]pyridine-3,6-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Ethyl Acetoacetate | HCID 8868 | — |
| 反応物 | HCID 178516394 | HCID 178516394 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 4-methyl-2,7-diphenyl-1H-pyrazolo[3,4-b]pyridine-3,6-dione | HCID 360316 | 34.5% |
反応手順
1-Phenyl-3-anilino-2-pyrazolin-5-one (25 g), ethyl acetoacetate (18 g) and acetic acid (150 ml) were heated to be refluxed for 6 hours. The reaction solution was diluted with water, and the resulting solid matter is crystallized from acetonitrile to obtain 10.9 g of 2,7-diphenyl-4-methylpyrazolo(3,4-b)pyridin-3,6-dione. It had a melting point of from 145 to 147° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06815152B2 |
| 出典データセット | uspto-grants-2004_11 |
| ORD ID | ord-138bd8c2fa4e4394a2ab02c073fd26da |
| 出典メモ | uspto-grants-2004_11 |