Ethanol → 2-(4-Methoxyphenyl)-1,1-dimethylethylamine
反応式
C[C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([CH3:14])([N+:11]([O-])=O)[CH3:10])=[CH:4][CH:3]=1.[H][H].[CH2:17]([OH:19])C>[Ni]>[CH3:10][C:9]([NH2:11])([CH3:14])[CH2:8][C:5]1[CH:6]=[CH:7][C:2]([O:19][CH3:17])=[CH:3][CH:4]=1参加物
5
実験手順
The 1-(4-methylphenyl)-2-methyl-2-nitropropane (1.3 g) was hydrogenated for 5 hours at 65 p.s.i. hydrogen in ethanol (30 mL) using 1.4 g of Raney nickel as catalyst. Removal of the catalyst by filtration and evaporation of the solvent yielded 1.15 g of 1,1-dimethyl-2-(4-methoxyphenyl)ethylamine as a clear oil.
後処理
- customRemoval of the catalyst
- filtrationby filtration and evaporation of the solvent
出典と根拠
- ORDレコード
- ord-618af30eb9674d129c1f7eac6211f749
- 出典データセット
- uspto-grants-2004_11
- 特許番号
- US06818660B2
反応ノート
読み込み中…