Hydrochloric Acid → 4-(5-Methoxy-1,2-benzisoxazolyl)piperidine hydrochloride
反応式
C([N:4]1[CH2:9][CH2:8][CH:7]([C:10]2[C:14]3[CH:15]=[C:16]([O:19][CH3:20])[CH:17]=[CH:18][C:13]=3[O:12][N:11]=2)[CH2:6][CH2:5]1)(=O)C.[ClH:21]>>[ClH:21].[CH3:20][O:19][C:16]1[CH:17]=[CH:18][C:13]2[O:12][N:11]=[C:10]([CH:7]3[CH2:8][CH2:9][NH:4][CH2:5][CH2:6]3)[C:14]=2[CH:15]=1参加物
3
実験手順
0.07 mol of 1-acetyl-4-(5-methoxy-1,2-benzisoxazolyl)piperidine and 110 ml of 6N HCl is refluxed for 6 hours and stand at room temperature to precipitate large amount of white deposit, which is recrystallized in ethanol to obtain 4-(5-methoxy-1,2-benzisoxazolyl)piperidine hydrochloride.
後処理
- customstand at room temperature
- customto precipitate large amount of white deposit, which
- customis recrystallized in ethanol
出典と根拠
- ORDレコード
- ord-3a0678ad8b5646cebc387c8570d35e4f
- 出典データセット
- uspto-grants-2014_02
- 特許番号
- US08653069B2
反応ノート
読み込み中…