化工社化工社 化学情報印刷レポート · 研究参考用
Sorbitol → L-enantiomer
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sorbitol | HCID 5780 | — |
| 反応物 | L-(-)-Sorbose | HCID 6904 | — |
| 反応物 | D-Sorbose | HCID 107428 | — |
| 反応物 | L-Ascorbic Acid | HCID 54670067 | — |
| 生成物 | L-enantiomer | HCID 11391247 | 95% |
反応手順
L-sorbose is an important intermediate for the synthesis of L-ascorbic acid (vitamin C) by the Reichstein method (see FIG. 1). When D-sorbitol is chemically oxidized, approximately a half of the product becomes D-sorbose, whereas when D-sorbitol is brought into contact with a microorganism having an SLDH activity, only an L-enantiomer is obtained in a yield of about 95%. Therefore, a fermentation method has been conventionally used for converting D-sorbitol to L-sorbose.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06825018B1 |
| 出典データセット | uspto-grants-2004_11 |
| ORD ID | ord-b6fad28536914bbda43461cdbe7d128a |
| 出典メモ | uspto-grants-2004_11 |