Hydrochloric Acid → 2-Methyl-1-phenylpiperaZine hydrochloride

HRID 2416657ノート

反応式

HRID 2416657 の反応式
[CH3:1][CH:2]1[N:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH2:6][CH2:5][N:4](C(OC(C)(C)C)=O)[CH2:3]1.[ClH:21]>C(OCC)(=O)C>[ClH:21].[C:8]1([N:7]2[CH2:6][CH2:5][NH:4][CH2:3][CH:2]2[CH3:1])[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 226330714-Boc-2-methyl-1-phenylpiperazine

生成物 1

HCID 226330592-Methyl-1-phenylpiperaZine hydrochloride

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

(±)-tert-Butyl 3-methyl-4-phenylpiperazine-1-carboxylate (142 mg) was dissolved in 4N hydrogen chloride in ethyl acetate (5 ml). After stirring for 15 minutes, the solvent was removed under reduced pressure to give the title compound as a slightly yellow solid.

後処理

  1. customthe solvent was removed under reduced pressure

出典と根拠

ORDレコード
ord-bad87fa887ec45f383499b68be82f86c
出典データセット
uspto-grants-2004_11
特許番号
US06825200B1

反応ノート

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