Chloranil → HCID 13338400、化合物
反応式
[CH3:1][N:2]1[C:6]2[C:7]3[N:8]([CH2:12][CH:13]([CH3:15])[N:14]=3)[C:9]([CH3:11])=[N:10][C:5]=2[C:4]([CH3:16])=[N:3]1.C1(Cl)C(=O)C(Cl)=C(Cl)C(=O)C=1Cl>C1(C)C(C)=CC=CC=1>[CH3:1][N:2]1[C:6]2[C:7]3[N:8]([CH:12]=[C:13]([CH3:15])[N:14]=3)[C:9]([CH3:11])=[N:10][C:5]=2[C:4]([CH3:16])=[N:3]1参加物
4
実験手順
A mixture of 2.4 g (0.011 mol) of 7,8-dihydro-1,3,5,8-tetramethyl-1H-imidazo[1,2-c]pyrazolo[3,4-e]pyrimidine and 5.6 g (0.022 mol) of chloranil in 400 ml of xylene is stirred under reflux four hours. The warm mixture is extracted with two 150 ml portions of 1N sodium hydroxide. The organic layer is separated, filtered, dried over MgSO4, and evaporated in vacuo. The solid residue is stirred in ether to give 1.2 g (50%) of the title compound, mp 198°-200°.
後処理
- temperatureunder reflux four hours
- extractionThe warm mixture is extracted with two 150 ml portions of 1N sodium hydroxide
- customThe organic layer is separated
- filtrationfiltered
- dry with materialdried over MgSO4
- customevaporated in vacuo
- stirringThe solid residue is stirred in ether
出典と根拠
- ORDレコード
- ord-0fdd88bbdf924c38ab59a019dacce00f
- 出典データセット
- uspto-grants-1984_09
- 特許番号
- US04469868
反応ノート
読み込み中…