p-Chlorothiophenol → HCID 23693160、化合物

HRID 2418333ノート

反応式

HRID 2418333 の反応式
[OH-].[K+:2].[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([SH:10])=[CH:6][CH:5]=1>CO>[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([S-:10])=[CH:6][CH:5]=1.[K+:2]

参加物

4

反応物 2

HCID 7815p-ChlorothiophenolHCID 14797Potassium Hydroxide

生成物 1

HCID 23693160HCID 23693160、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒2 回

実験手順

To a solution of potassium hydroxide (2.5 g.) in methanol (30 ml.) was dissolved 4-chlorobenzenethiol (6.5 g.), and methanol was distilled off to give potassium 4-chlorobenzenethiolate. To this product were added ethyl 2-(2-nitro-3-chlorophenyl)acetate (10 g.) and dimethylformamide (50 ml.) and stirred for 1.5 hours at 100° C. The reaction mixture was poured into water (300 ml.) and extracted with diethyl ether. The extract was washed with water, dried over magnesium sulfate and then evaporated under reduced pressure. The residue was recrystallized from a mixture of benzene and n-hexane to give yellow needles of the captioned compound (9.9 g.). mp 77° to 79° C.

後処理

  1. distillationwas distilled off

出典と根拠

ORDレコード
ord-a11aed851c7b4ca3851e97ab0fcdc7b8
出典データセット
uspto-grants-1984_09
特許番号
US04472433

反応ノート

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