関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 3-(Ethoxymethylene)pentane-2,4-dione | HCID 240418 | — |
| 反応物 | 3-Amino-2,5,6-trichlorobenzoic acid | HCID 19834569 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | HCID 178467925 | HCID 178467925 | 741.6% |
反応手順
46.8 g (0.3 mole) of methyl 1-methylcarbonyl-2-ethoxyvinyl ketone were added dropwise to a suspension of 48.1 g (0.02 mole) of 3-amino-2,5,6-trichlorobenzoic acid in 100 ml of toluene. The mixture was heated for 2 hours to 80° C and was then cooled to 10° C, and the precipitate was filtered off. After digesting with acetonitrile, 52 g (74% of theory) of 3-[2,2-bis-(methylcarbonyl)-vinylamino]-2,5,6-trichlorobenzoic acid were obtained in the form of colourless crystals of melting point 242°-244° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04104049 |
|---|
| 出典データセット | uspto-grants-1978_08 |
|---|
| ORD ID | ord-d46c7e3906b448a3880bd5b79d6480f2 |
|---|
| 出典メモ | uspto-grants-1978_08 |
|---|
