Dimethyl N-cyanodithioiminocarbonate → HCID 20316728、化合物
反応式
[NH2:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[C:11]([OH:12])=[CH:10][CH:9]=[CH:8][N:7]=1.[CH3:13][S:14][C:15](=[N:18][C:19]#[N:20])SC>C(O)C>[C:19]([NH:18][C:15](=[N:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[C:11]([OH:12])=[CH:10][CH:9]=[CH:8][N:7]=1)[S:14][CH3:13])#[N:20]参加物
4
実験手順
A solution of 2-((2-aminoethyl)thiomethyl)-3-hydroxypyridine (7.5 g) in ethanol was added slowly to a solution of dimethylcyanodithioimidocarbonate (6.0 g) in ethanol, with stirring at room temperature. The mixture was set aside overnight at room temperature. Filtration afforded N-cyano-N'-[2-((3-hydroxy-2-pyridyl)methylthio)-ethyl]-S-methylisothiourea (4.85 g), m.p. 192°-194°. Recrystallisation from aqueous ethanol gave fine needles, m.p. 196°-198°.
後処理
- filtrationFiltration
出典と根拠
- ORDレコード
- ord-2c00e250f5414a818971b4f5f22314c8
- 出典データセット
- uspto-grants-1978_08
- 特許番号
- US04104382
反応ノート
読み込み中…