3,4-Dimethylbenzaldehyde → HCID 178425638、化合物
反応式
[CH3:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[CH3:10])[CH:5]=O.[IH:11].[NH2:12][NH:13][C:14]([NH:16][CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[NH:15]>C(O)C>[IH:11].[CH2:17]([NH:16][C:14]([NH:13][N:12]=[CH:5][C:4]1[CH:7]=[CH:8][C:9]([CH3:10])=[C:2]([CH3:1])[CH:3]=1)=[NH:15])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1参加物
4
実験手順
A mixture of 2.68 g. of 3,4-dimethylbenzaldehyde and 5.84 g. of 1-amino-3-benzylguanidine hydroiodide [W. J. Finnegan, R. A. Henry and E. Lieber, J. Org. Chem., 18, 779 (1953)] in 30 ml. of 66% aqueous ethanol is heated under reflux for 3 hours and then allowed to cool and crystallize. Filtration gives nearly colorless crystals which are recrystallized from aqueous ethanol, giving the desired product as cream-colored crystals, m.p. 183°-185° C.
後処理
- addition