2-(Trifluoromethyl)aniline → N-[2-(Trifluoromethyl)phenyl]butanamide

HRID 2419818ノート

反応式

HRID 2419818 の反応式
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:9]=[CH:8][CH:7]=[CH:6][C:4]=1[NH2:5].[C:12](Cl)(=[O:16])[CH2:13][CH2:14][CH3:15]>>[F:1][C:2]([F:10])([F:11])[C:3]1[CH:9]=[CH:8][CH:7]=[CH:6][C:4]=1[NH:5][C:12](=[O:16])[CH2:13][CH2:14][CH3:15]

参加物

3

反応物 2

HCID 69222-(Trifluoromethyl)anilineHCID 8855Butyryl chloride

生成物 1

HCID 3557464N-[2-(Trifluoromethyl)phenyl]butanamide収率 52.8%

実験手順

Using the procedure of Step A of Example 6, 32.2 g of o-trifluoromethylaniline and 23.44 g of butyryl chloride were reacted to obtain 24.4 g of N-(2-trifluoromethylphenyl)-butanamide melting at 76° C which was used as is for the next step.

後処理

  1. customwere reacted

出典と根拠

ORDレコード
ord-ca30d8ec23274c73aee119d371e178b7
出典データセット
uspto-grants-1978_08
特許番号
US04107310

反応ノート

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