2-(1-Methylethylidene)cyclohexanone → HCID 12220944、化合物

HRID 2419980ノート

反応式

HRID 2419980 の反応式
[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9][CH2:8][NH+:7]=1.[C:16](=[C:19]1[CH2:24][CH2:23][CH2:22][CH2:21][C:20]1=O)([CH3:18])[CH3:17]>CN(C)C=O.C(O)C>[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH3:18][C:16]1[C:19]2[CH2:24][CH2:23][CH2:22][CH2:21][C:20]=2[N+:7]2[CH2:8][CH2:9][C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][C:15]=3[C:6]=2[CH:17]=1

参加物

5

反応物 2

HCID 262522-(1-Methylethylidene)cyclohexanoneHCID 20312280HCID 20312280、化合物

生成物 1

HCID 12220944HCID 12220944、化合物

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 6228Dimethylformamide溶媒

実験手順

3,4-Dihydroisoquinolinium perchlorate (4.6 g) and 2-isopropylidenecyclohexanone (3 g) were dissolved in dimethylforamide (12 ml) and refluxed for 12 hours. The reaction mixture was cooled, diluted with ethanol, and filtered. The product was purified by recrystallization from methanol. Yield 3 g; m.p. 205°.

後処理

  1. temperaturerefluxed for 12 hours
  2. temperatureThe reaction mixture was cooled
  3. filtrationfiltered
  4. customThe product was purified by recrystallization from methanol

出典と根拠

ORDレコード
ord-27135de797264b0ea899086a2a137f3e
出典データセット
uspto-grants-1978_08
特許番号
US04108667

反応ノート

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