3,3-Bis(ethoxycarbonyl)bicyclo[3.2.0]heptane → Bicyclo[3.2.0]heptane-3,3-dicarboxylic acid
反応式
C([O:3][C:4]([C:6]1([C:13]([O:15]CC)=[O:14])[CH2:12][CH:11]2[CH:8]([CH2:9][CH2:10]2)[CH2:7]1)=[O:5])C.CO.O>[OH-].[K+]>[CH:8]12[CH2:9][CH2:10][CH:11]1[CH2:12][C:6]([C:13]([OH:15])=[O:14])([C:4]([OH:5])=[O:3])[CH2:7]2参加物
4
実験手順
A solution of 10.3 g of 3,3-bis(ethoxycarbonyl)bicyclo[3.2.0]heptane in 68 ml of 16% potassium hydroxide in 1:1 methanol-water was refluxed for 16 hr under argon. The solvents were removed in vacuo and the residue dissolved in a minimum amount of water. The solution was acidified with concentrated hydrochloric acid and the precipitated acid isolated by vacuum filtration to yield 6.9 g of bicyclo[3.2.0]heptane-3,3-dicarboxylic acid as a white solid, mp 161°-170°.
後処理
- customThe solvents were removed in vacuo
- dissolutionthe residue dissolved in a minimum amount of water
- customthe precipitated acid isolated by vacuum filtration
出典と根拠
- ORDレコード
- ord-5158d76f21ea44edad38045e00017cf8
- 出典データセット
- uspto-grants-1978_08
- 特許番号
- US04108892
反応ノート
読み込み中…