Hydrochloric Acid → HCID 20313024、化合物

HRID 2420109ノート

反応式

HRID 2420109 の反応式
[CH2:1]([C:8]1[CH:9]=[CH:10][C:11]([C:14]([OH:16])=[O:15])=[N:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[CH2:18](O)[CH3:19]>>[CH2:1]([C:8]1[CH:9]=[CH:10][C:11]([C:14]([O:16][CH2:18][CH3:19])=[O:15])=[N:12][CH:13]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

4

反応物 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 30428422-Pyridinecarboxylic acid, 5-(phenylmethyl)-

生成物 1

HCID 20313024HCID 20313024、化合物

実験手順

2.0 Grams of 5-benzylpicolinic acid were suspended in 25 ml. of ethanol. The resulting suspension was saturated with hydrogen chloride gas under ice-cooling. After reflux for three hours, the reaction solution was concentrated under reduced pressure. Ether was added thereto to form crystals. The crystals were then recrystallized from a solvent comprising a mixture of acetone/ether to obtain 1.7 g of ethyl 5-benzylpicolinate of a melting point of 109°~111° C.

後処理

  1. temperaturecooling
  2. temperatureAfter reflux for three hours
  3. concentrationthe reaction solution was concentrated under reduced pressure
  4. additionEther was added
  5. customto form crystals
  6. customThe crystals were then recrystallized from a solvent comprising
  7. additiona mixture of acetone/ether

出典と根拠

ORDレコード
ord-60ae81fb857d426eba9005aab5bb7eeb
出典データセット
uspto-grants-1978_08
特許番号
US04109000

反応ノート

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