Ammonia → 2-Phenylpyrimidin-4-ol
反応式
[C:1]1([C:7]2[N:12]=[C:11](N)[CH:10]=[CH:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.ClC1C=CN=C(C2C=CC=CC=2)N=1.N.C(N)(=N)C1C=CC=CC=1.C(CC([O-])=O)=[O:38].[Na+]>>[C:1]1([C:7]2[NH:12][C:11](=[O:38])[CH:10]=[CH:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1参加物
6
実験手順
Ruhemann et al. [Chem. Ber. 30, 2022 (1897)] prepared 2-phenyl-4-pyrimidinamine by reacting 4-chloro-2-phenylpyrimidine with ammonia. The 4-chloro-2-phenylpyrimidine had been prepared in two steps by first reacting benzamidine with sodium formylacetate to produce 2-phenyl-4-pyrimidone and then reacting the latter with phosphorus oxychloride.
出典と根拠
- ORDレコード
- ord-d9b38b34620041ccbb939bd11d3ae244
- 出典データセット
- uspto-grants-1978_08
- 特許番号
- US04109092
反応ノート
読み込み中…