Hydrochloric Acid → HCID 20311931、化合物
反応式
[C:1]1([CH:7]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[N:8]2[CH2:12][CH:11]([CH2:13][O:14][C:15]3[CH:20]=[CH:19][C:18]([CH2:21][CH2:22][CH3:23])=[CH:17][C:16]=3[O:24][CH3:25])[O:10]C2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1(C(C2C=CC=CC=2)N2CC(C[Cl:45])OC2)C=CC=CC=1.COC1C=C(CCC)C=CC=1[O-].[Na+].Cl>>[ClH:45].[CH3:25][O:24][C:16]1[CH:17]=[C:18]([CH2:21][CH2:22][CH3:23])[CH:19]=[CH:20][C:15]=1[O:14][CH2:13][CH:11]([OH:10])[CH2:12][NH:8][CH:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1参加物
5
実験手順
3-Diphenylmethyl-5-(2-methoxy-4-n-propyl-phenoxymethyl)oxazolidine from 3-diphenylmethyl-5-chloromethyl-oxazolidine and sodium 2-methoxy-4-n-propyl-phenolate; this product is hydrolysed with alcoholic-aqueous hydrochloric acid to give 1-(2-methoxy-4-n-propyl-phenoxy)-2-hydroxy-3-diphenylmethylamino-propane hydrochloride with a melting point of 108°-110°.