Hydrochloric Acid → 12-Aminododecanoic acid amide hydrochloride
反応式
C(OC(=O)[NH:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19](=[O:21])[NH2:20])(C)(C)C.[ClH:23]>>[ClH:23].[NH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([NH2:20])=[O:21]参加物
3
実験手順
[(11-Carbamoylundecyl)carbamic acid tert-butyl ester (7) (0.085 g, 0.27 mmol) was treated with HCl (4 M in dioxane, 2 mL, 8 mmol) at room temperature for 14 hours. The reaction mixture was concentrated in vacuo and further dried under high vacuum. The white solid (0.068 g, 99%) was used directly without further purification: m/z (ESI) 215 [C12H26N2O+H]+.
後処理
- concentrationThe reaction mixture was concentrated in vacuo
- customfurther dried under high vacuum
- customThe white solid (0.068 g, 99%) was used directly without further purification
出典と根拠
- ORDレコード
- ord-90c188506b9f43b9985ee6ead1b629bc
- 出典データセット
- uspto-grants-2011_06
- 特許番号
- US07956059B2
反応ノート
読み込み中…