Ethyl 2-chloro-2-(methylsulfanyl)acetate → (3-Bromo-8-fluoro-quinolin-6-yloxy)-methylsulfanyl-acetic acid ethyl ester
反応式
[Br:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([CH:11]=1)=[CH:9][C:8]([OH:12])=[CH:7][C:6]=2[F:13].[CH2:14]([O:16][C:17](=[O:22])[CH:18](Cl)[S:19][CH3:20])[CH3:15]>>[CH2:14]([O:16][C:17](=[O:22])[CH:18]([O:12][C:8]1[CH:9]=[C:10]2[C:5](=[C:6]([F:13])[CH:7]=1)[N:4]=[CH:3][C:2]([Br:1])=[CH:11]2)[S:19][CH3:20])[CH3:15]参加物
3
実験手順
In a similar procedure to Stage 2, Step 1 of Example 5, 3-bromo-8-fluoro-quinolin-6-ol was reacted with chloro-methylsulfanyl-acetic acid ethyl ester to give (3-Bromo-8-fluoro-quinolin-6-yloxy)-methylsulfanyl-acetic acid ethyl ester.
出典と根拠
- ORDレコード
- ord-871a4f090ccf44719e64597f54e88aaf
- 出典データセット
- uspto-grants-2011_06
- 特許番号
- US07956188B2
反応ノート
読み込み中…