Ammonium Acetate → 3-(2-Fluoro-4-iodo-phenylamino)-2-methyl-isonicotinamide
反応式
[F:1][C:2]1[CH:7]=[C:6]([I:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10]1[C:18]([CH3:19])=[N:17][CH:16]=[CH:15][C:11]=1[C:12](O)=[O:13].C([O-])(=O)C.[NH4+:24]>>[F:1][C:2]1[CH:7]=[C:6]([I:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10]1[C:18]([CH3:19])=[N:17][CH:16]=[CH:15][C:11]=1[C:12]([NH2:24])=[O:13]参加物
3
実験手順
3-(2-Fluoro-4-iodo-phenylamino)-2-methyl-isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.2 mmol of 3-[(2-fluoro-4-iodophenyl)amino]-2-methyl-isonicotinic acid and 0.4 mmol of ammonium acetate. LC/MS [1.85 min; 372 (M+1)].
後処理
- customLC/MS [1.85 min; 372 (M+1)]
出典と根拠
- ORDレコード
- ord-664890e59e0e4beea4cbbb2cb55ecdf2
- 出典データセット
- uspto-grants-2011_06
- 特許番号
- US07956191B2
反応ノート
読み込み中…