4-Toluenesulfonyl chloride → 2-[(2-tert-Butyl-1,1-dioxido-3-oxo-5-phenyl-2,3-dihydroisothiazol-4-yl)amino]ethyl 4-methylbenzenesulfonate

反応式

[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8](OCCCNC2C(=O)N(C(C)(C)C)S(=O)(=O)C=2C2C=CC=CC=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[C:34]([N:38]1[C:42](=[O:43])[C:41]([NH:44][CH2:45][CH2:46][OH:47])=[C:40]([C:48]2[CH:53]=[CH:52][CH:51]=[CH:50][CH:49]=2)[S:39]1(=[O:55])=[O:54])([CH3:37])([CH3:36])[CH3:35].CC1C=CC(S(Cl)(=O)=O)=CC=1>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([O:47][CH2:46][CH2:45][NH:44][C:41]2[C:42](=[O:43])[N:38]([C:34]([CH3:37])([CH3:35])[CH3:36])[S:39](=[O:54])(=[O:55])[C:40]=2[C:48]2[CH:53]=[CH:52][CH:51]=[CH:50][CH:49]=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1