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O-Cresol → Methyl 3-(4-((3-(2-methylphenoxy)benzyl)oxy)phenyl)propanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | O-Cresol | HCID 335 | — |
| 反応物 | 3-Bromobenzaldehyde | HCID 76583 | — |
| 反応物 | Benzenepropanoic acid, 4-hydroxy-, methyl ester | HCID 79706 | — |
| 反応物 | [3-(2-Methylphenoxy)phenyl]methanol | HCID 23082899 | — |
| 生成物 | Methyl 3-(4-((3-(2-methylphenoxy)benzyl)oxy)phenyl)propanoate | HCID 23083053 | — |
反応手順
The title compound was synthesized in the same manner as in Example 277 from methyl 3-(4-hydroxyphenyl)propanoate and [3-(2-methylphenoxy)phenyl]methanol (synthesized in the same manner as in Reference Example 201 from o-cresol and 3-bromobenzaldehyde (mixture with side product)) (preparative HPLC (gradient cycle A) was used for purification). colorless oil (yield 28%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07960369B2 |
| 出典データセット | uspto-grants-2011_06 |
| ORD ID | ord-3476422b94804a7e9a1fd304ed91910e |
| 出典メモ | uspto-grants-2011_06 |