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Anthranilic Acid → 2-(2-Methoxy-4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}phenyl)-3-methylquinazolin-4(3H)-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Anthranilic Acid | HCID 227 | — |
| 反応物 | Methylamine | HCID 6329 | — |
| 反応物 | 1-Bromo-3-chloropropane | HCID 8006 | — |
| 反応物 | 4-Hydroxy-2-Methoxybenzaldehyde | HCID 519541 | — |
| 反応物 | (S)-3-Methylpiperidine | HCID 641100 | — |
| 反応物 | (R)-Mandelate | HCID 5460269 | — |
| 生成物 | 2-(2-Methoxy-4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}phenyl)-3-methylquinazolin-4(3H)-one | HCID 11524620 | — |
反応手順
The entitled compound was obtained according to the method of Example 1 but starting from anthranilic acid, methylamine, 4-hydroxy-2-methoxybenzaldehyde, 1-chloro-3-bromopropane and (3S)-3-methylpiperidine.(R)-mandelate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07960394B2 |
| 出典データセット | uspto-grants-2011_06 |
| ORD ID | ord-d9c3f9ea6a474542981abb432eb5cb2e |
| 出典メモ | uspto-grants-2011_06 |