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1-Methyl-3-(2',2',2'-trifluoroethyl)imidazolium triflate → 1-methyl-3-(2',2',2'-trifluoroethyl)imidazolium N-(trifluoromethanesulfonyl)-trifluoroacetamide

HRID 2423020
ノート
印刷プレビュー

反応式

HRID 2423020 の反応式
[O-]S(C(F)(F)F)(=O)=O.[CH3:9][N+:10]1[CH:14]=[CH:13][N:12]([CH2:15][C:16]([F:19])([F:18])[F:17])[CH:11]=1.[F:20][C:21]([F:33])([F:32])[S:22]([NH:25][C:26](=[O:31])[C:27]([F:30])([F:29])[F:28])(=[O:24])=[O:23].[Na]>O>[F:32][C:21]([F:20])([F:33])[S:22]([NH:25][C:26](=[O:31])[C:27]([F:28])([F:29])[F:30])(=[O:24])=[O:23].[CH3:9][N+:10]1[CH:14]=[CH:13][N:12]([CH2:15][C:16]([F:18])([F:17])[F:19])[CH:11]=1
参加物実験手順後処理出典と根拠反応ノート

参加物

4

反応物 2

HCID 866047831-Methyl-3-(2',2',2'-trifluoroethyl)imidazolium triflateHCID 86604785sodium N-(trifluoromethanesulfonyl)trifluoroacetamide

生成物 1

HCID 866047841-methyl-3-(2',2',2'-trifluoroethyl)imidazolium N-(trifluoromethanesulfonyl)-trifluoroacetamide

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

1-Methyl-3-(2′,2′,2′-trifluoroethyl)imidazolium triflate (10 mmol) and water (10 ml) were placed in a reaction vessel, and a solution of sodium N-(trifluoromethanesulfonyl)trifluoroacetamide (2.94 g, 11 mmol) and water (3 ml) were added thereto while stirring. The mixture was then stirred for 15 minutes. The lower oil layer was separated, and this layer was repeatedly washed with water. The obtained oil product was dehydrated using a vacuum pump at 110° C. for 3 hours, and 1-methyl-3-(2′,2′,2′-trifluoroethyl)imidazolium N-(trifluoromethanesulfonyl)-trifluoroacetamide (compound 12) was obtained (yield 2.87 g, 70%). When further purification is required, the oil product may be dissolved in a small amount of ethyl acetate, and a large amount of ether may be added thereto to separate the oil product and the product may be dried. Alternatively, when the product is colored, it may be treated with active carbon. Physical property, elemental analysis and spectral data of the compound 12 are shown in Table 8.

後処理

  1. stirringThe mixture was then stirred for 15 minutes
  2. customThe lower oil layer was separated
  3. washthis layer was repeatedly washed with water
  4. customat 110° C.
  5. customfor 3 hours

出典と根拠

ORDレコード
ord-90738b81615f49d695b751db84a14236
出典データセット
uspto-grants-2011_06
DOI
10.6084/m9.figshare.5104873.v1
特許番号
US07960554B2

反応ノート

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