4-Fluoroaniline → N-(Benzimidazol-2-yl)-4-fluoroaniline

HRID 2423034ノート

反応式

HRID 2423034 の反応式
Cl[C:2]1[NH:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[F:11][C:12]1[CH:18]=[CH:17][C:15]([NH2:16])=[CH:14][CH:13]=1>>[N:6]1[C:5]2[CH:7]=[CH:8][CH:9]=[CH:10][C:4]=2[NH:3][C:2]=1[NH:16][C:15]1[CH:17]=[CH:18][C:12]([F:11])=[CH:13][CH:14]=1

参加物

3

反応物 2

HCID 97314-FluoroanilineHCID 785722-Chlorobenzimidazole

生成物 1

HCID 923845N-(Benzimidazol-2-yl)-4-fluoroaniline

実験手順

The title compound was prepared from 2-chlorobenzimidazole and 4-fluoroaniline by Procedure A. The product was isolated by filtration to give the title compound as a hydrochloride salt (solid, mp 215-216° C.). MS(ES+) m/z 228 ([M+1]+, 100).

後処理

  1. customThe product was isolated by filtration

出典と根拠

ORDレコード
ord-7a9ba1d4483b4e619ae49de577a4378d
出典データセット
uspto-grants-2011_06
特許番号
US07960561B2

反応ノート

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