Piperidine, 1-(2-chloroethyl)-, hydrochloride → HCID 11258656、化合物
反応式
COC1C=CC(CC2C=CC=C(OC)C=2)=C(C=1)OC1C=CC(O)=CC=1.Cl.ClCCN1CCCCC1.C[O:37][C:38]1[CH:39]=[CH:40][C:41]([CH2:60][C:61]2[CH:66]=[CH:65][CH:64]=[C:63]([O:67]C)[CH:62]=2)=[C:42]([CH:59]=1)[O:43][C:44]1[CH:58]=[CH:57][C:47]([O:48][CH2:49][CH2:50][N:51]2[CH2:56][CH2:55][CH2:54][CH2:53][CH2:52]2)=[CH:46][CH:45]=1>>[OH:67][C:63]1[CH:62]=[C:61]([CH:66]=[CH:65][CH:64]=1)[CH2:60][C:41]1[CH:40]=[CH:39][C:38]([OH:37])=[CH:59][C:42]=1[O:43][C:44]1[CH:45]=[CH:46][C:47]([O:48][CH2:49][CH2:50][N:51]2[CH2:52][CH2:53][CH2:54][CH2:55][CH2:56]2)=[CH:57][CH:58]=1参加物
4
実験手順
Synthesized from 4-[5-methoxy-2-(3-methoxybenzyl)phenoxy]phenol and 1-(2-chloroethyl)piperidine hydrochloride according to an analogous synthetic method to Preparation Example 40, 1-{2-{4-[5-methoxy-2-(3-methoxybenzyl)phenoxy]phenoxy}ethyl}piperidine (228 mg) was used according to an analogous synthetic method to Example 364 to provide the title compound (105 mg).