Tetracaine Hydrochloride → HCID 86603141、化合物
反応式
[CH3:1][CH2:2][CH2:3][CH2:4][NH:5][C:6]1[CH:7]=[CH:8][C:9]([C:12]([O:14][CH2:15][CH2:16][N:17]([CH3:19])[CH3:18])=[O:13])=[CH:10][CH:11]=1.Cl.[C@@H:21]1([O:52][P:53]([OH:56])([OH:55])=[O:54])[C@@H:26]([O:27][P:28]([OH:31])([OH:30])=[O:29])[C@H:25]([O:32][P:33]([OH:36])([OH:35])=[O:34])[C@@H:24]([O:37][P:38]([OH:41])([OH:40])=[O:39])[C@@H:23]([O:42][P:43]([OH:46])([OH:45])=[O:44])[C@H:22]1[O:47][P:48]([OH:51])([OH:50])=[O:49]>O>[CH3:1][CH2:2][CH2:3][CH2:4][NH:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]([O:14][CH2:15][CH2:16][N:17]([CH3:19])[CH3:18])=[O:13])=[CH:8][CH:7]=1.[CH:23]1([O:42][P:43]([OH:46])([OH:45])=[O:44])[CH:24]([O:37][P:38]([OH:40])([OH:41])=[O:39])[CH:25]([O:32][P:33]([OH:35])([OH:36])=[O:34])[CH:26]([O:27][P:28]([OH:31])([OH:30])=[O:29])[CH:21]([O:52][P:53]([OH:56])([OH:55])=[O:54])[CH:22]1[O:47][P:48]([OH:50])([OH:51])=[O:49]参加物
4
実験手順
1.0 g tetracaine hydrochloride (3.33 mmol) was dissolved in 40 mL water and with vigorous stirring, 20.5 mL of the phytic acid solution of Example 1 was added. After another 30 min of stirring, the precipitate was centrifuged and washed with water. The final products were in the form of white powder. The solubility of the complex in different buffers is shown below.