化工社化工社 化学情報印刷レポート · 研究参考用
4-tert-Butyl-1,3-thiazol-2-amine → N-(4-tert-butylthiazol-2-yl)-3-(3,4-difluorophenyl)-6,7-dihydropyrano[4,3-c]pyrazole-1(4H)-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-tert-Butyl-1,3-thiazol-2-amine | HCID 2734202 | — |
| 反応物 | (S)-3-(3,4-difluorophenyl)-N-(3,3-dimethyl-1-(methyl-amino)-1-oxobutan-2-yl)-6,7-dihydropyrano[4,3-c]pyrazole-1(4H)-carboxamide | HCID 46834697 | — |
| 生成物 | N-(4-tert-butylthiazol-2-yl)-3-(3,4-difluorophenyl)-6,7-dihydropyrano[4,3-c]pyrazole-1(4H)-carboxamide | HCID 46830659 | — |
反応手順
Compound 56 was prepared according to the procedure described for the synthesis of compound 28 by replacing tert-leucine methylamide with 2-amino-4-tert-butylthiazole. LCMS (+ESI) m/z=419.2 [M+H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08653127B2 |
| 出典データセット | uspto-grants-2014_02 |
| ORD ID | ord-5ae4b90e57fe4e0e8d17b3622fcd3b34 |
| 出典メモ | uspto-grants-2014_02 |