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HRID 2426699作成日：2026年10月27日

2,5-Dichlorobenzonitrile → 1-(4-Chloro-2-cyanophenyl)piperidine-4-carboxylic Acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide

https://huagongshe.com/reaction/2426699

反応式

関与物質

役割名称HCID仕込み量
反応物2,5-DichlorobenzonitrileHCID 89000—
反応物Piperidine-4-carboxylic acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amideHCID 67147939—
生成物1-(4-Chloro-2-cyanophenyl)piperidine-4-carboxylic Acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amideHCID 58867765—

反応手順

Piperidine-4-carboxylic acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide was reacted with 2,5-dichlorobenzonitrile as described in example 323. This resulted in the product with the molecular weight of 452.00 (C25H30CIN5O); MS (ESI): 452 (M+H+).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07968550B2
出典データセットuspto-grants-2011_06
ORD IDord-fdc40c582f2c4fe0bbc596f9e63bb0d8
出典メモuspto-grants-2011_06