Bromine → 3-Amino-7-bromo-4-chloro-2-naphthoic acid
反応式
[NH2:1][C:2]1[C:3]([C:13]([OH:15])=[O:14])=[CH:4][C:5]2[C:10]([C:11]=1[Cl:12])=[CH:9][CH:8]=[CH:7][CH:6]=2.[Br:16]Br>C(O)(=O)C>[NH2:1][C:2]1[C:3]([C:13]([OH:15])=[O:14])=[CH:4][C:5]2[C:10]([C:11]=1[Cl:12])=[CH:9][CH:8]=[C:7]([Br:16])[CH:6]=2参加物
4
実験手順
To a mixture of 0.56 g of 3-amino-4-chloro-2-naphthoic acid and 20 ml of acetic acid was added dropwise 0.4 g of bromine at room temperature. The resulting mixture was stirred at room temperature for 1 hour. A deposited precipitate was collected by filtration, and the resulting solid was washed successively with acetic acid and ethyl acetate to obtain 0.36 g of 3-amino-7-bromo-4-chloro-2-naphthoic acid of the formula:
後処理
- filtrationA deposited precipitate was collected by filtration
- washthe resulting solid was washed successively with acetic acid and ethyl acetate
出典と根拠
- ORDレコード
- ord-d50bb266cd874cd4bdfc0ab03a3c758a
- 出典データセット
- uspto-grants-2011_06
- 特許番号
- US07968573B2
反応ノート
読み込み中…