2-(2-Chloro-4-nitro-phenylsulfanyl)-benzothiazole-5-carbonitrile → 2-(4-Amino2-chlorophenylsulfanyl)-benzothiazole-5-carbonitrile
反応式
[Cl:1][C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[CH:5]=[CH:4][C:3]=1[S:11][C:12]1[S:13][C:14]2[CH:20]=[CH:19][C:18]([C:21]#[N:22])=[CH:17][C:15]=2[N:16]=1.O.O.[Sn](Cl)(Cl)(Cl)Cl>>[NH2:8][C:6]1[CH:5]=[CH:4][C:3]([S:11][C:12]2[S:13][C:14]3[CH:20]=[CH:19][C:18]([C:21]#[N:22])=[CH:17][C:15]=3[N:16]=2)=[C:2]([Cl:1])[CH:7]=1参加物
3
実験手順
The title compound was prepared using the method of example 270, starting with 2-(2-chloro-4-nitro-phenylsulfanyl)-benzothiazole-5-carbonitrile (263) (1.59 g, 4.58 mmol), tin chloride dihydrate (Aldrich, 5.18 g, 22.9 mmol). Compound 275 (1.35 g, 93%) was obtained as a yellowish solid.
後処理
- customThe title compound was prepared
出典と根拠
- ORDレコード
- ord-49d4c530ad194b259dc7473acd9344dc
- 出典データセット
- uspto-grants-2011_06
- 特許番号
- US07968567B2
反応ノート
読み込み中…