化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → 3-[(Pyrrolidin-1-yl)methyl]benzoic acid hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Methyl 3-(pyrrolidin-1-ylmethyl)benzoate | HCID 53429637 | — |
| 生成物 | 3-[(Pyrrolidin-1-yl)methyl]benzoic acid hydrochloride | HCID 18525874 | — |
反応手順
A solution of 3-pyrrolidin-1-ylmethyl-benzoic acid methyl ester (800 mg, 3.6 mmol) in aqueous 25% hydrochloric acid (15 mL) was stirred at 90° C. for 4 hours. The solvent was evaporated affording the title compound as brown oil (quantitative) that was used as such for the next step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07968583B2 |
| 出典データセット | uspto-grants-2011_06 |
| ORD ID | ord-8cda23d7871149ac9cf399e9f52cbf07 |
| 出典メモ | uspto-grants-2011_06 |