Benzoyl Peroxide → HCID 67252371、化合物
反応式
[CH3:1][O:2][C:3](=[O:13])[C:4]1[C:9]([CH3:10])=[CH:8][C:7]([F:11])=[CH:6][C:5]=1[I:12].[Br:14]NC(=O)CCC(N)=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[CH3:1][O:2][C:3](=[O:13])[C:4]1[C:5]([I:12])=[CH:6][C:7]([F:11])=[CH:8][C:9]=1[CH2:10][Br:14]参加物
5
実験手順
A mixture of 4-fluoro-2-iodo-6-methyl-benzoic acid methyl ester (1.14 g, 3.74 mmol), N-bromosuccinamide (0.796 g, 4.5 mmol), and benzoyl peroxide (0.024 g, 0.146 mmol) in carbon tetrachloride (50 mL) was heated at reflux until majority of ester was consumed (as analyzed by GC/MS). The resulting mixture was filtered, the filtrate was concentrated to afford 2-bromomethyl-4-fluoro-6-iodo-benzoic acid methyl ester. The material was used without further purification
後処理
- temperaturewas heated
- customwas consumed (as analyzed by GC/MS)
- filtrationThe resulting mixture was filtered
- concentrationthe filtrate was concentrated
出典と根拠
- ORDレコード
- ord-491d573530a54bdeac5ccf6a96f819b0
- 出典データセット
- uspto-grants-2011_06
- 特許番号
- US07968570B2
反応ノート
読み込み中…