(3-Methyl-2-nitrophenyl)phenylamine → 3-Methyl-N1-phenylbenzene-1,2-diamine

関与物質

反応手順

A mixture of (3-methyl-2-nitrophenyl)phenylamine (931 mg, 4.08 mmol) and 10% Pd/C (465 mg) in EtOAc (20 mL) was degassed with a stream of nitrogen and stirred at RT under a hydrogen atmosphere for 4 h. The suspension was then filtered through a PTFE frit and the filtrate was concentrated in vacuo affording 3-Methyl-N1-phenylbenzene-1,2-diamine as an off-white solid (763 mg, 94%). LCMS: RT 3.37 min [M+H]+ 199.0.

情報源と証拠