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Potassium Cyanide → Ethyldiisopropyl-ammonium
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Cyanide | HCID 9032 | — |
| 反応物 | Diisopropylethylamine | HCID 81531 | — |
| 反応物 | 4-Methylene-3-oxabicyclo[3.2.1]octan-2-one | HCID 12993977 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | Ethyldiisopropyl-ammonium | HCID 3411517 | — |
| 生成物 | 4-Hydroxybicyclo[3.2.1]oct-3-en-2-one | HCID 12993980 | — |
反応手順
Analogously to Example P1, 1.38 g (10 mmol) of 4-methylene-3-oxabicyclo[3.2.1]octan-2-one are stirred over a period of 12 hours in the presence of 1.29 g (10 mmol) of Hünig's base and 0.13 g of potassium cyanide in 10 ml of acetonitrile. Solid components (potassium salts) are filtered off and the filtrate is evaporated to dryness to yield the ethyldiisopropyl-ammonium salt of 4-hydroxybicyclo[3.2.1]oct-3-en-2-one in the form of a resin.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06855831B2 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-db5741c94adc43d09fa3ea6ec262eab3 |
| 出典メモ | uspto-grants-2005_02 |